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Non-invasive imaging method spots cancer at the molecular level

The researchers combined multiphoton microscopy with automated image and statistical analysis algorithms to distinguish between healthy and diseased tissue. In this image, collected in a completely label free, noninvasive manner, collagen is colored green while ovarian metastatic cell clusters are presented in red. Credit: Dimitra Pouli, Thomas Schnelldorfer, and Irene Georgakoudi, Tufts University and Lahey […]

Raman spectroscopy poised to make thyroid cancer diagnosis less invasive

Credit: CC0 Public Domain Researchers have demonstrated that an optical technique known as Raman spectroscopy can be used to differentiate between benign and cancerous thyroid cells. The new study shows Raman spectroscopy’s potential as a tool to improve the diagnosis of thyroid cancer, which is the ninth most common cancer with more than 50,000 new […]

System to image the human eye corrects for chromatic aberrations

These are images of the smallest cone photoreceptors in the retina, about 2 microns wide. Coloration was added to represent the different wavelengths of light used to capture the images after compensating chromatic aberration. Credit: Xiaoyun Jiang, Ramkumar Sabesan, University of Washington Researchers report a new imaging system that cancels the chromatic optical aberrations present […]

Theory, topology and potential applications

Credit: CC0 Public Domain In almost all situations, even in a vacuum, light cannot travel endlessly without dissipating. Pulses of light known as solitons that propagate along fibres for long distances without changing their shape or losing focus have found applications in data transmission, but even these gradually dissipate unless the medium they travel through […]

Recovering color images from scattered light

Researchers have created a method that takes light from colored numerals (top left) that has been scattered by a mostly opaque surface (top center) and uses its ‘speckle’ patterns and a coded aperture to reconstruct the image in five different frequencies (bottom row) before combining them into a final image (top right). Credit: Michael Gehm, […]

SLAP microscope smashes speed records

A new microscope breaks a long-standing speed limit, recording footage of brain activity 15 times faster than scientists once believed possible. It gathers data quickly enough to record neurons’ voltage spikes and release of chemical messengers over large areas, monitoring hundreds of synapses simultaneously—a giant leap for the powerful imaging technique called two-photon microscopy. The […]